Synthases/Synthetases

Under this framework, modifications to desired clinical outcomes should be considered

Under this framework, modifications to desired clinical outcomes should be considered. mathematical framework to study imatinib resistance arising in chronic myeloid leukemia (CML) patients [61, 66] and to address the…

Continue ReadingUnder this framework, modifications to desired clinical outcomes should be considered

Based on the central role of NK and CD8 T cell signaling in cholangiocyte injury and on the increased expression of perforin and granzymes in livers of patients with biliary atresia [10, 11], we hypothesized that this perforin-granzyme system is required for epithelial injury of bile ducts

Based on the central role of NK and CD8 T cell signaling in cholangiocyte injury and on the increased expression of perforin and granzymes in livers of patients with biliary…

Continue ReadingBased on the central role of NK and CD8 T cell signaling in cholangiocyte injury and on the increased expression of perforin and granzymes in livers of patients with biliary atresia [10, 11], we hypothesized that this perforin-granzyme system is required for epithelial injury of bile ducts

1B)

1B). before I/R. Pharmacological preconditioning: provided agents had been perfused for 2 5-min cycles before I/R, aside from V1-1 (PKC inhibitor) implemented during the whole 30-min reperfusion following 20-min ischemia.…

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