In disagreement with this T-cell hypothesis is the observation that mice deficient in the T-cell-expressed inflammatory cytokines gamma interferon and tumor necrosis factor or the T-cell-polarizing cytokine interleukin 12, although more susceptible, nevertheless resolve infection with with identical (tumor necrosis factor and gamma interferon) or only moderately delayed (interleukin 12) kinetics (13, 28)
In disagreement with this T-cell hypothesis is the observation that mice deficient in the T-cell-expressed inflammatory cytokines gamma interferon and tumor necrosis factor or the T-cell-polarizing cytokine interleukin 12, although…