Consequently the interest in free 25(OH)D and free 1, 25(OH)2D levels has increased substantially because of their relevance to disease declares in which the binding proteins are markedly modified such as liver disease and protein losing nephropathy, normal physiologic states such as pregnancy, and genetic variations in binding proteins that may affect their affinity intended for the hormone in question [24]
Consequently the interest in free 25(OH)D and free 1, 25(OH)2D levels has increased substantially because of their relevance to disease declares in which the binding proteins are markedly modified such…